Blister machine BLU 400

Max. 400 blisters/min.
Max. format area 195 x 284 mm

Uhlmann BLU 400: Blister machine for the gentle handling of liquid dose products

The BLU 400 handles the pharmaceutical packaging of ampoules, syringes, vials, bottles, cartridges, or pens in blister packs. The compact packaging machine meets all the essential requirements of the pharmaceutical market for the secondary packaging of liquid dose products. As a fully automated packaging system, the BLU 400 offers a convincing performance based on reliable, gentle product handling and flexible, cost-efficient packaging.

The BLU 400 for the gentle packaging of liquid dose products

The packaging of liquid dose products is no easy task in general as the small glass receptacles are susceptible to damage, particularly when glass-glass or glass-metal contact occurs. Should a product break, cleaning is much more laborious than with solids. This factor places high demands on the packaging machine.

The Uhlmann Blister machine BLU 400 meets all the key requirements of the secondary packaging of liquid dose products:

  • Gentle: Very careful handling avoids damage to the liquid dose products, e.g., minimum drop heights in the feeder, or integrated product position control in the press-in and sealing station.
  • Straightforward: Intuitive operation of the blister packaging machine and easy, guided format changeovers with the SmartControl operating system.
  • Flexible: Whether feeder, fill section, transfer, or cartoner – boundless optional configurations of the packaging system cover all product requirements.
  • Efficient: Optimum format utilization on account of product and blister rotation, which leads to minimum waste and maximum machine output.

Media-Gallery

 Heating and forming station

Heating and forming station

The heating and forming station of the blister packaging machine BLU 400 has three heating zones. These allow the gradual heating of the forming material to the specified forming temperature for the respective type of film.

 LiPro feeder

LiPro feeder

LiPro stands for liquid product. The proven feeder is designed to handle ampoules, vials, cartridges, and bottles.

 Press-in station

Press-in station

Product position monitoring is integrated into the press-in station. The two-step press-in function requires less force, which minimizes the risk of product damage.

 Syringe feeder SyPro

Syringe feeder SyPro

SyPro stands for syringe product. The feeder is responsible for the reliable handling and placement of syringes into blister packs.

 Platen sealing and cooling station: During production

Platen sealing and cooling station: During production

The layout of the platen sealing and cooling station of the packaging machine for liquids is optimized to suit the packaging process. Functions are also integrated to protect the susceptible liquid dose products against heat, such as the automatic positioning of cooling plates in the event of a machine stop.

 Platen sealing and cooling station: In the event of machine stop

Platen sealing and cooling station: In the event of machine stop

The layout of the platen sealing and cooling station of the packaging machine for liquids is optimized to suit the packaging process. Functions are also integrated to protect the susceptible liquid dose products against heat, such as the automatic positioning of cooling plates in the event of a machine stop.

 Punching station

Punching station

The punching station of the Uhlmann BLU 400 operates with high precision. Various modes of punching are available, which help to reduce waste and increase output.

 Blister transfer to the cartoner

Blister transfer to the cartoner

The blister packs can be rotated 90° when transferred to the cartoner. This allows optimum utilization of the web width.

 BLU 400 and C 2305 for the packaging of ampoules, vials, or cartridges

BLU 400 and C 2305 for the packaging of ampoules, vials, or cartridges

By combining the BLU 400 and the Cartoner C 2305, Uhlmann offers an optimally coordinated packaging system for the production of unsealed clamp packs and their packaging in cartons.

 BLU 400 and C 2305 for syringes

BLU 400 and C 2305 for syringes

Together, the BLU 400 and the Cartoner C 2305 form a system that is ideal for the placement of syringes into sealed or unsealed blisters and their packaging in cartons.

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Technical Data

Blister machine BLU 400

Max. output

400 blisters/min.

Sealing principle

platen sealing

Mode of operation

1- to 8-lane

Scope of application

liquid dose products

Max. format area [index x width]

195 x 284 mm

Max. forming depth

42 mm

Max. reel diameter

forming material 800 mm, lid material 400 mm

Processable forming materials

PET, PET/PE, PET-G, PVC

Processable lid materials

Al, PET, paper

The Blister machine BLU 400 in detail

Gentle feeding and placement into the transparent blister pack

The feed plate of the LiPro feeder – LiPro stands for liquid product – transports the upright liquid dose products, e.g., ampoules, vials, cartridges, and bottles, up to 30 millimeter in diameter, in micro-steps to the feeding roller. The roller turns the products to a horizontal pick-up position ready for a 4-axle robot system to take over placement into the blister pockets. The roller then continues to rotate, ensuring that it is completely empty prior to the next filling cycle. This way, the following products are not damaged and no machine stoppage is caused. The SyPro feeder – SyPro stands for syringe product – is available for syringes with diameters ranging between 6.5 and 26 millimeter.


Alternate pressing into place in the blister pack

Before the products are pressed into the clamp pack, their correct positioning in the blister is controlled mechanically. The liquid dose products are then alternately pushed into the blister pockets. The two-step press-in function requires less force, which minimizes the risk of product damage.


Integrated camera system

In addition to monitoring product presence, an Uhlmann camera inspection system can check the color ring coding or carry out similar inspection tasks, thus controlling the reliable elimination of faulty products. In the case of sealed blister packs, inspection of the products to ensure correct, level positioning in the blister is carried out prior to applying the lid foil.


Cooling of heat-sensitive products

Sealed blisters are cooled in the platen sealing and cooling station immediately after the sealing process in order to protect the contents from heat. The products are also protected against heat radiating from the sealing plate should the packaging process be interrupted. In such a case, a water-cooled plate automatically moves into position over the blisters in the sealing station.


Optimum format utilization

As the BLU 400 operates with a product rotation function, full use can be made of the web width. In other words, products can be positioned both lengthwise and crosswise to the running direction of the web. The blister sizes ranges from 20 x 60 millimeters to 195 x 284 millimeters. In this context, it is not only the feeder that can position the products lengthways or crossways: the transfer of the filled blisters to the cartoner is correspondingly designed. A gripper places the blisters on a rotary table that turns 180° or 270° to allow insertion of the blisters in the carton.


Fast format changeovers and easy cleaning

The fast format changeovers and easy cleaning have a positive impact on the overall performance of the Blister machine BLU 400. The C-shaped layout of the stations used by the Uhlmann engineers, which has proven successful over the years in other machines, allows a straightforward changeover from one format to another. The few, light-weight format parts are readily exchanged without tools. All the surfaces are easy to clean. In the case of the fill section, for example, all the cables and control elements are fully enclosed.


Flexible machine design to meet every need

The compact packaging machine BLU 400 is of modular design. Should a pharmaceutical manufacturer wish to handle a liquid dose product of a completely different format, or handle another product, the fill section can be exchanged on site. Either clamp packs or sealed blisters can be processed. The reel supports for the forming material and the lid foil   can be integrated into the machine or positioned externally depending on customer requirements. A manual loading position can also be added to the fill section area.

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